Antifungal polyene macrolide that preferentially binds to fungal ergosterol which alters cellular permeability.

An azole most commonly used for topical treatment of candidiasis:

Polyene macrolide only used topically, due to systemic toxicity; active against most Candida species--most commonly used for suppression of local candidal infection.

Of ketoconazole, itraconazole, and fluconazole--most likely to cause increased arrhythmogenic effects of astemizole or terphidine

Inhibition of fungal squalene epoxidase is this antifungal drug's mechanism of action:

More serious adverse effects: itraconazole (azole) or flucytosine (pyrimidine analogue)

Most potent of the presently available anti-fungal azoles:

Azole most likely to get into the cerebral spinal fluid (CSF):

Given by i.v. administration, the drug of choice for nearly all life-threatening mycotic infections--usually used as the initial induction regimen

Topical allylamine(s) used for treating tinea cruris and tinea corporis: