Medical Pharmacology Practice Questions: Adrenergy Autonomic Pharmacology

Immediate biosynthetic precursor of epinephrine:
1. isoproterenol
2. doapmine
3. metaraminol
4. norepinephrine
5. L-DOPA
The magnitude of the cardiovascular response to norepinephrine is increased by cocaine because:
1. cocaine increases conversion of norepinephrine to phenylephrine
2. cocaine inhibits norepinephrine reuptake
3. cocaine decreases N.E. metabolism by MAO
4. cocaine increases N.E. receptor number
5. cocaine decreases cholinergic receptor number
Increases both magnitude of the blood pressure increase due to phenylephrine and the heart rate decrease due to methacholine:
1. timolol (Blocadren)
2. mecamylamine (Inversine)
3. clonidine (Catapres)
4. atropine
5. nitroprusside sodium (Nipride)
Drug causes pupillar dilation with no effect on accommodation:
1. pilocarpine (Pilocar)
2. atropine
3. phenoxybenzamine (Dibenzyline)
4. neostigmine (Prostigmin)
5. phentolamine (Regitine)
Prevents blood pressure reduction seen with isoproterenol (Isuprel):
1. atropine
2. esmolol (Brevibloc)
3. propranolol (Inderal)
4. phentolamine (Regitine)
5. phenylephrine (Neo-Synephrine)
Physiological effects associated with isoproterenol (Isuprel):
1. increased peripheral resistance
2. increased GI motility
3. increased blood glucose
4. decreased heart rate
5. bronchoconstriction
Albuterol (Ventolin,Proventil):
1. significant heart rate increase
2. decreases myocardial contractility
3. α-adrenoceptor antagonist
4. bronchodilation
5. by I.V. injection only
Therapeutic use of esmolol (Brevibloc):
1. bronchial asthma
2. positive inotrope in CHF
3. antiarrhythmic drug
4. renal vasodilator
5. antihypertensive
Isoproterenol (Isuprel): cardiopulmonary effects:
1. increases peripheral resistance
2. positive inotropism
3. positive chronotropism
4. A & C
5. B & C
ß-2 selective agonist:
1. metaproterenol (Alupent)
2. epinephrine
3. phenylephrine (Neo-Synephrine)
4. phentolamine (Regitine)
5. labetalol (Trandate, Normodyne)