Medical Pharmacology Practice Test Questions: Drugs Used in Managing Congestive Heart Failure

Potassium sparing diuretic:
1. furosemide (Lasix)
2. triamterene (Dyrenium)
3. chlorothiazide (Diuril)
4. mannitol (Osmitrol)
5. torsemide (Demadex)
Increased urinary output in a congestive heart failure patient who has been started on digoxin (Lanoxin, Lanoxicaps) is most likely due to:
1. renovascular dilatation
2. increased renal perfusion
3. decreased post glomerular arteriolar tone
4. a direct effect on renal sodium transport
5. a decrease in vagal tone to the kidney
Potassium sparing diuretic:
1. chlorothiazide (Diuril)
2. bumetanide (Bumex)
3. amiloride (Midamor)
4. mannitol (Osmitrol)
5. furosemide (Lasix)
Primarily an arterial vasodilator that may be useful in management of congestive heart failure:
1. isosorbide dinitrate (Isordil, Sorbitrate)
2. minoxidil (Loniten)
3. lisinopril (Prinvivil, Zestril)
Digitalis-induced bradycardia in the normal heart is due to:
1. decreased conduction through the AV node
2. increased vagal tone
3. increased sympathetic tone
4. decrease in fluid load
5. peripheral vasodilation
Digitalis-effect on vascular resistance in congestive heart failure patients:
1. vascular resistance increases
2. vascular resistance decreases
Digitalis-induced diuresis in edematous patients is mainly due to:
1. renal vasodilation
2. increased post-glomerular arteriolar tone
3. increased cardiac output
4. decreased heart rate
5. blockade of the sodium-potassium transporter
Drug interaction that may reduce digitalis absorption:
1. quinidine gluconate (Quinaglute, Quinalan)
2. cholestyramine (Questran, Questran Light)
3. norepinephrine
An example of a positive inotropic drug that acts by inhibiting myocardial phosphodiesterase.
1. triamcinolone (Aristocort)
2. amrinone (Inocor)
3. ouabain
4. tranylcypromine (Parnate)
5. dopamine (Intropin)
Cardiac effects of. digoxin (Lanoxin, Lanoxicaps) include:
1. increased heart rate
2. increased automaticity
3. decreased velocity of contraction
4. increased conduction through the AV node
5. decreased cardiac output
Angiotensin II receptor antagonist:
1. captopril (Capoten)
2. isosorbide dinitrate (Isordil, Sorbitrate)
3. losartin (Cozaar)
4. nitroprusside sodium (Nipride)
5. hydralazine (Apresoline)
Calcium channel blocker with marked negative inotropic cardiac effects:
1. nifedipine (Procardia, Adalat)
2. diltiazem (Cardiazem)
3. amlodipine (Norvasc)
4. amrinone (Inocor)
5. labetalol (Trandate, Normodyne)
Positive inotropic agent that not only stimulates beta-1, beta-2, alpha-1, alpha-2 receptors but also acts as a vasodilator to reduce aortic impedance (afterload).
1. isoproterenol (Isuprel)
2. norepinephrine
3. dopamine (Intropin)
4. dobutamine (Dobutrex)
5. phenylephrine (Neo-Synephrine)
Loop diuretic useful both in acute and chronic management of congestive heart failure:
1. chlordiazepoxide (Librium)
2. chlorthalidone (Hygroton)
3. bumetanide (Bumex)
4. ethacrynic acid (Edecrin)
5. spironolactone (Aldactone)
Digoxin (Lanoxin, Lanoxicaps) clinical uses:
1. atrial fibrillation
2. atrial flutter
3. congestive heart failure
4. A & C
5. A, B & C
Useful in treating arrhythmias associated with digitalis toxicity:
1. lidocaine (Xylocaine)
2. potassium
3. both
4. neither
Effects of digitalis glycosides on the heart include:
1. increased conduction velocity through the AV node
2. decreased refractory period of the AV node
3. positive inotropic effects
4. positive chronotropic effects
5. A & C
Positive inotropic drug are not classified as a cardiac glycoside:
1. metoprolol (Lopressor)
2. prazosin (Minipress)
3. amrinone (Inocor)
4. methacholine (Provocholine)
5. quinidine gluconate (Quinaglute, Quinalan)