Medical Pharmcology: Parkinson's Disease Practice Questions

Neurologic dysfunction is associated with this recessively-inherited disorder of copper metabolism:
1. Parkinson's disease
2. Wilson's disease
3. Huntington's chorea
4. Tourette's syndrome
5. Thyrotoxicosis
A drug-induced dyskinesia -- typically induced by long-term use of phenothiazine antipsychotics;in adults, may not be reversible
1. Parkinsonian syndrome
2. akathisia
3. tardive dyskinesia
4. acute dystonia
5. perioral tremor
Drug(s) which will alleviate acute dystonic reactions following the first doses of a phenothiazine:
1. benztropine
2. diazepam
3. biperiden
4. A & C
5. A, B & C
Dominantly-inherited: associated with progressive chorea & dementia, typically beginning in adulthood --possibly due to overactivity of dopaminergic nigrostriatal pathways
1. Wilson's disease
2. Tourette's syndrome
3. Huntington's chorea
4. Parkinsonism
Essential tremor: receptor system most likely to be involved given that propranolol or metoprolol may improve the syndrome.
1. GABA receptors
2. glutamate receptors
3. adrenergic receptors
4. adenosine receptors
5. muscarinic receptors
Neurotransmitter system(s) that may be involved in Parkinson's disease:
1. Dopaminergic
2. Cholinergic
3. both
4. neither
Drug-induced severe Parkinsonism associated with the inadvertent synthesis of this pro-toxin.
1. selegiline
2. MPTP
3. primidone
4. amantadine
5. all of the above
Acetylcholine-blocking agents, despite being helpful in managing Parkinson's disease, should be avoided in patients with:
1. angle closure glaucoma
2. prostatic hyperplasia
3. pyloric stenosis
4. paralytic ileus
5. all of the above
Antimuscarinic drug(s) used in management of Parkinson's disease include(s):
1. orphenadrine
2. amitriptyline
3. selegiline
4. amantadine
5. levodopa
In lower doses, this agent can be used to treat hyperprolactinemia:
1. amantadine
2. levodopa
3. bromocriptine
4. selegiline
5. phenothiazine