90% of body serotonin found here | | |
Can deplete stores serotonin | | |
Primary enzyme that metabolizes serotonin | | |
Major serotonin coupling mechanism | | |
Odansetron: serotonin receptor subtype | | |
Gastrointestinal effect: of excessive serotonin production | | |
Nonbenzodiazepine anxiolytic: thought to work through serotonin systems | | |
5-HT1D: agonist-- effective in treating acute migraine headache | | |
Serotonin antagonist: major clinical application is antagonizing smooth muscle effects of carcinoid tumor | | |
5-HT3 antagonist: primary clinical use is prevention of nausea and vomiting associated with cancer chemotherapy | | |