Medical Pharmacology: Physiology and Pharmacology of Thyroid Pathophysiology and Pharmacology Practice Questions

Myxedema coma:
1. increased sensitivity of the respiratory center
2. hyperthermia
3. CO2 retention
4. hyperglycemia
5. none of the above
Thyroxine toxicity:
1. symptom in children: slowed growth
2. in adults -- tachycardia
3. directly related to hormone level
4. B & C
5. A, B & C
Hypothyroidism:
1. always occurs with thyroid enlargement (goiter)
2. associated with low free thyroxine and elevated serum TSH
3. most common cause: hypothalamic pathology
4. A & B
5. none of the above
Agent of choice to block sympathetic nervous system manifestations of thyrotoxicosis:
1. reserpine
2. guanethidine
3. propranolol
4. trimethaphan
5. phenoxybenzamine
Associated with radioactive iodine used for treating thyrotoxicosis:
1. rapidly absorbed
2. follicular disruption
3. does not appear to pause radiation induced leukemia or neoplasia
4. should not give minister to nursing mothers since radioactive iodine is excreted in breast milk
5. all of the above
Concerning a patient with myxedema and coronary vascular disease:
1. myxedema may be beneficial in this patient with respect to cardiac disease
2. effort should be made to rapidly correct the myxedema state
3. both
4. neither
Treatment of choice for patients with very large thyroid glands or multinodular goiters.
1. triiodothyronine
2. thyroxine
3. propylthiouracil alone
4. subtotal thyroidectomy, following antithyroid drug treatment (until euthyroid)
5. methimazole alone
Due to excessive ingestion of thyroid hormone (for example in foods):
1. subacute thyroiditis
2. thyrotoxicosis factitia
3. myxedema coma
4. Graves' disease
5. the the bone
Treatment of thyroid storm:
1. propranolol if patient has asthma
2. propylthiouracil
3. hydrocortisone
4. A & B
5. B & C
Antithyroid drug therapy:
1. most useful in older patients with large glands and advanced disease
2. disease may undergo spontaneous remission
3. methimazole reduces activated thyroid hormone levels more quickly
4. A & B
5. A, B & C