Question # 5 (Multiple Answer) Factors that influence the passive movement of drugs down a concentration gradient:
(A) drug concentration differences on either side of the barrier (e.g. membrane)
(B) thickness of the diffusion pathway
(C) mobility of the drug molecule in the medium of the diffusion path (permeability)
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Question # 7 (Multiple Answer) Concerning renal drug excretion:
(A) almost all drugs are filtered by the glomerulus
(B) a lipid-soluble, filtered drug will likely be reabsorbed by passive diffusion
(C) pH partitioning (the drug is ionized at the urinary pH) enhances excretion
(D) weak acids are excreted faster in alkaline urinary pH
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