Anesthesia Pharmacology Chapter
25: Drugs that Affect Coagulation Practice Questions
Click on the correct answer.
Spontaneous arresting of bleeding from blood vessel:
- vasospasm
- viscous metamorphosis
- hemostasis
- fibrinolysis
- coagulation
Platelet sticking to exposed damage blood vessel collagen:
- vasospasm
- platelet aggregation
- fibrinolysis
- platelet adhesion
Initial type of thrombus associated with formation in high-pressure arteries:
- white thrombus
- red thrombus
- both
- neither
Synthesized within platelets; promotes thrombogenesis and vasoconstriction
- prostacyclin (PGI2)
- thromboxane A2 (TXA2)
- both
- neither
More likely associated with venous thrombi:
- local occlusive ischemia
- embolization distant to thrombi location
- both
- neither
Mechanism(s) of action of anticoagulant drugs:
- synthesis inhibition
- inhibition of activated clotting factor activity
- both
- neither
Coagulation protein inhibitors -- protease inhibitors
- alpha2-macroglobulin
- alpha2-antiplasmin
- antithrombin III
- alpha1-antiprotease
- all the above
Expectable cause of disseminated intravascular coagulation (DIC):
- Crohn's disease
- myocardial infarction
- abruptio placentae
- Wilson's disease
- Christmas factor deficiency
Inhibitor of fibrinolysis
- t-PA
- urokinase
- streptokinase
- aminocaproic acid
Limits thrombosis extension by proteolytic fibrin digestion:
- plasminogen
- proaccelerin
- plasmin
- Christmas factor
- Stuart-Prower factor