Anesthesia Pharmacology: Pharmacology of Adrenergic Drugs
Choose the correct answer for each question.
Metabolic action(s) associated with catecholamines and sympathomimetic drugs:
- Reduction in rate of liver glycogenolysis
- Reduction in rate of muscle glycogenolysis.
- Both
- Neither
Catecholamine and sympathetic drug action(s) in the central nervous system:
- Appetite suppression
- Increase in psychomotor activity
- Both
- Either
Catecholamines and sympathomimetic drugs exhibit this/these effects on neurotransmitter release:
- Inhibition of neurotransmitter release
- Promotion of neurotransmitter release
- Both
- Neither
Catecholamine and sympathomimetic drug(s) direct effect/effects on the heart:
- Positive chronotropic effect
- Positive inotropic effect
- Both
- Neither
Catecholamine and sympathomimetic drug classification:
- Direct-acting
- Indirect-acting
- Mixed-acting
- A & B
- B & C
- A & C
- A, B & C
Phenylephrine exhibits selectivity for the
α1 adrenergic receptor.
- True
- False
The drug terbutaline exhibits selectivity for the
β1 adrenergic receptor.
- True
- False
Receptor/receptors that may be activated by epinephrine administration:
-
α1
-
α2
-
β1
-
β2
-
β3
- A & B
- C, D & E
- A, B, C, D & E (all receptor sites)
Example of an "indirect acting" adrenergic agonist:
- Phenylephrine
- Cocaine
- Oxymetazoline
- Isoproterenol
Example of indirect-acting adrenergic agonist that promotes catecholamine release as its principal mechanism.
- Clonidine
- Amphetamine
- Norepinephrine
- Dobutamine