Anesthesia Pharmacology: Sedative-Hypnotic Drug Practice
Questions
1 / 20
Preferable to barbiturates for hypnosis:
Most likely to decrease GABA-receptor-mediated synaptic inhibition while inhibiting the NMDA glutamate receptor and potentiating of the action of serotonin:
Ethanol pharmacology:
More likely to be an effective muscle relaxant:
Likely to activate GABA Type A receptors while inhibiting the AMPA system:
Receptor system which probably mediates the action of buspirone (BuSpar):
Primary receptor system implicated in the action of benzodiazepines:
Most important ion conductance affected by the state of the GABA receptor system:
Reduction the cerebral edema following surgery; useful in head injury cases and management of cerebral ischemia:
More likely susceptible to acetaminophen (Tylenol, Panadol) toxicity
Reduction of hypoxic respiratory drive: This is a barbiturate effectt that occurs at doses about three times higher than required for pharmacological hypnosis
Benzodiazepines when used in the endoscopy setting:
Benzodiazepine effects if used as preanesthetic medication
Relatively safe agent for management of generalized anxiety disorder with limited abuse potential:
Ethanol metabolism:
Example/examples of benzodiazepines:
More likely to be effective in managing mild anxiety of less likely to be effective in treating panic disorder
Anesthesia implication/implications: chronic ethanol use
Initial ethanol metabolic step:
Factor/factors promoting the use of benzodiazepines: