Anesthesia Pharmacology: Coagulation

Spontaneous arresting of bleeding from blood vessel:
1. vasospasm
2. viscous metamorphosis
3. hemostasis
4. fibrinolysis
5. coagulation
Platelet sticking to exposed damage blood vessel collagen:
1. vasospasm
2. platelet aggregation
3. fibrinolysis
4. platelet adhesion
Initial type of thrombus associated with formation in high-pressure arteries:
1. white thrombus
2. red thrombus
3. both
4. neither
Synthesized within platelets; promotes thrombogenesis and vasoconstriction
1. prostacyclin (PGI2)
2. thromboxane A2 (TXA2)
3. both
4. neither
More likely associated with venous thrombi:
1. local occlusive ischemia
2. embolization distant to thrombi location
3. both
4. neither
Mechanism(s) of action of anticoagulant drugs:
1. synthesis inhibition
2. inhibition of activated clotting factor activity
3. both
4. neither
Coagulation protein inhibitors -- protease inhibitors
1. alpha2-macroglobulin
2. alpha2-antiplasmin
3. antithrombin III
4. alpha1-antiprotease
5. all the above
Expectable cause of disseminated intravascular coagulation (DIC):
1. Crohn's disease
2. myocardial infarction
3. abruptio placentae
4. Wilson's disease
5. Christmas factor deficiency
Inhibitor of fibrinolysis
1. t-PA
2. urokinase
3. streptokinase
4. aminocaproic acid
Limits thrombosis extension by proteolytic fibrin digestion:
1. plasminogen
2. proaccelerin
3. plasmin
4. Christmas factor
5. Stuart-Prower factor