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IPS Clinical Uses (Inhibitor of Protein Synthesis Drugs)
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Chloramphenicol: (Chloromycetin)
Serious rickettsial infections (typhus or Rocky Mountain spottend fever) in children under 8 (when tetracyclines are contraindicated)
Alternative treatment for bacterial meningitis due to a very penicillin-resistant pneumococcal isolate
Meningococcal infections in patients with significant penicillin hypersensitivity.
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Used in combination with other drugs to treat gastric and duodenal ulcer casue by Helicobacter pylori.
Erythromycin is the drug of choice in treatment corynebacterial infections (diphtheria, corynebacterial sepsis, erythrasma)
In respiratory, neonatal, ocular or genital chlamydia infections
Community-acquired pneumonia because its broad spectrum of treatment of action allows effective treatment of pneumoncoccus, Mycoplasma and Legionella
Erythromycin: penicillin-substitute for patients allergic to penicillin
Clindamycin: (Cleocin)
Primary, important indication for clindamycin: severe anaerobic infections due to Bacterioides and other anaerobes in mixed infections.
Prophylaxis: Clindamycin instead of erythromycin for endocarditis prior to dental procedures on patients who have valvular diseas
Clindamycin + primaquine: effective alternative to trimethoprim-sulfamethoxazole (Bactrim) in treating moderate to moderately-severe Pneumocystis carinii pneumonia in AIDS patients.
Clindamycin (Cleocin): useful in treating AIDS-related CNS toxoplasmosis in combination with pyrimethamine (Daraprim).
Chloramphenicol: (Chloromycetin)
Serious rickettsial infections (typhus or Rocky Mountain spottend fever) in children under 8 (when tetracyclines are contraindicated)
Alternative treatment for bacterial meningitis due to a very penicillin-resistant pneumococcal isolate
Meningococcal infections in patients with significant penicillin hypersensitivity.
Used in combination with other drugs to treat gastric and duodenal ulcer casue by Helicobacter pylori.
Erythromycin is the drug of choice in treatment corynebacterial infections (diphtheria, corynebacterial sepsis, erythrasma)
In respiratory, neonatal, ocular or genital chlamydia infections
Community-acquired pneumonia because its broad spectrum of treatment of action allows effective treatment of pneumoncoccus, Mycoplasma and Legionella
Erythromycin: penicillin-substitute for patients allergic to penicillin
Clindamycin: (Cleocin)
Primary, important indication for clindamycin: severe anaerobic infections due to Bacterioides and other anaerobes in mixed infections.
Prophylaxis: Clindamycin instead of erythromycin for endocarditis prior to dental procedures on patients who have valvular diseas
Clindamycin + primaquine: effective alternative to trimethoprim-sulfamethoxazole (Bactrim) in treating moderate to moderately-severe Pneumocystis carinii pneumonia in AIDS patients.
Clindamycin (Cleocin): useful in treating AIDS-related CNS toxoplasmosis in combination with pyrimethamine (Daraprim).
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