Medical Pharmacology: Antiviral Drugs

**"Incidence of Myocardial Infarction in the HOPS Cohort"⁸**

Incidence of MI risk in the cohort described in reference 8.

**"Risk of Myocardial Infarction According to Exposure to Protease Inhibitors and Nonnucleoside Reverse-Transcriptase Inhibitors"⁹**

This figure, which corresponds to panel B of Figure 2 in reference 9, describes the adjust relative rates of myocardial infarction according to the cumulative exposure to protease inhibitors and nonnucleoside reverse-transcriptase inhibitors.⁹

References
Flexner C Antiretroviral Agents and Treatment of HIV Infection, Chapter 59 in Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12th edition (Brunton LL Chabner BA Knollmann BC, eds; Brunton LL, ed; Blumenthal DK Murri N Hilal-Dandan R, assoc eds, Knollmann BC, consulting ed, on-line edition) The McGraw-Hill Companies, 2011. Fauci AS Lane HC Chapter 189, Human Immunodeficiency Virus Disease: AIDS and Related Disorders, in Harrison's Online (Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo, Eds.), Harrison's Principles of Internal Medicine, 18th edition, The McGraw-Hill Companies, Inc. 2012. Longo DL Fauci AS 188, The Human Retroviruses, in Harrison's Online (Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo, Eds.), Harrison's Principles of Internal Medicine, 18th edition, The McGraw-Hill Companies, Inc. 2012. Lewis W Currie PF Chapter 93 HIV/AIDS and the Cardiovascular System (in Hurst's The Heart, 13 e Fuster V, Walsh RA Harrington RA, eds; Hunt AS King III SB Nash IS Prystowsky EN Roberts R Rose E, Assoc eds) The McGraw-Hill Companies, Inc 2011. Thienemann F Sliwa K Rockstroh JK HIV and the heart: the impact of antiretroviral therapy: a global perspective. Eur Heart J 34(46): 3538-3546 Dec. 2013 http://www.ncbi.nlm.nih.gov/pubmed/24126882 Woster PM Chapter 43: Antiviral Agents and Protease Inhibitors in Foye's Principles of Medicinal Chemistry 6e, Lemke, TL Williams DA, eds; Roche VG Zito SW, asst eds) Wolters Kluwer\|Lippincott Williams & Wilkins 1219-1225, 2008. The Data Collection on Adverse Events of Anti-HIV DRugs (DAD) Study Group. Combination Antiretroviral Therapy and the Risk of Myocardial Infarction. 349(21): 1993-2003, 2003. Holmberg SD Moorman AC Williamson JM Tong TC Ward DJ Wood KC Greenberg AE Janssen RS and the HIV Outpatient Study (HOPS) Investigators Lancet 360: 1747-1748, 2002. The DAD Study Group. Class of antiretroviral drugs and the risk of myocardial infarction. N Engl J Med 356: 1723-1735. 2007.

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