Medical Pharmacology: Antiviral Drugs Practice Questions

Medical Pharmacology: Antiviral Drugs Practice Questions

**Cidofovir (Vistide)**

**Trifluridine (Viroptic)**

Click on the correct answer.

Anti-herpesvirus drug(s):
1. Idoxuridine
2. Valacyclovir
3. Both
4. Neither
Anti-herpesvirus drug(s):
1. Acyclovir (Sitavig, Zovirax)
2. Cidofovir (Vistide)
3. Trifluridine (Viroptic)
4. A & B
5. B & C
6. A & C
7. A, B & C
Anti-influenza drug:
1. Foscarnet (Foscavir)
2. Oseltamivir (Tamiflu)
3. Both
4. Neither
IV administration
1. Amantadine (Symadine and others)
2. Oseltamivir (Tamiflu)
3. Peramivir (Rapivab)
Anti-influenza drug usually given by inhalation:
1. Peramivir (Rapivab)
2. Zanamivir (Relenza)
3. Rimantadine (Flumadine)
IV acyclovir appropriate as first-line treatment for herpes encephalitis, neonatal HSV infection and for herpes simplex viral infection in in immunocompromised patient.
1. True
2. False
In patients resistant to acyclovir herpes simplex viral infections or Varicella-zoster viral infections, IV foscarnet as an alternative may be appropriate.
1. True
2. False
Management of herpetic keratoconjunctivitis treatment:
1. Ganciclovir (topical)
2. Trifluridine (topical)
3. Both
4. Neither
Herpes proctitis: oral acyclovir
1. True
2. False
Appropriate for treatment of orolabial herpes:
1. Acyclovir
2. Docosanol
3. Penciclovir
4. A & B
5. B & C
6. A & C
7. A, B & C

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Source Material:
- Acosta EP Chapter 62 Antiviral Agents (Nonretroviral) in Goodman & Gilman's: The Pharmcological Basis of Therapeutics, 14e, (Brunton LL Knollmann BC eds) McGraw-Hill Education, 2023.
- Safrin S Chapter 49 Antiviral Agents in Basic & Clinical Pharmacology (Katzung BG, Editor; Vanderah TW, Associate editor) 15e McGraw Hill 2021.
- Li JZ Coen DM Chapter 38 Pharmacology of Viral Infections in Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy 4e (Golan DE Armstong EJ Armstrong AW, eds) Wolters Kluwer 2017.
- Waller DB Sampson AP Section 11 Chemotherapy in Medical Pharmacology & Therapeutics Elsevier 2018.
- Burchum JR Rosenthal LD Chapter 97 Antiviral Agents I: Drugs for Non-HIV Viral Infections in Lehne's Pharmacology for Nursing Care Elsevier 2022.
- Waller DB Sampson AP Section 11: Chapter 51 Chemotherapy of infections in Medical Pharmacology & Therapeutics Elsevier 2018.
- Benavides S Bahal O'Mara N Nahata MC Chapter 79 Viral Infections in Applied Therapeutics: The Clinical Use of Drugs (Zeind C, Carvalho MG Cheng JW Zaiken K Lapointe T, eds} Wolters Kluwer, 2024.