Medical Pharmacology Chapter 5: Pharmacology of Adrenergic Drugs

Epinephrine administration:
1. Increases hematocrit
2. Decreases plasma protein concentration
3. Both
4. Neither
Epinephrine administration decreases circulating plasma volume as protein-free fluid is displaced to extracellular volume.
1. True
2. False
Most typical epinephrine doses:
1. Do not notably change plasma volume
2. Do not notably change packed red cell volume normally.
3. Both
4. Neither
Effects of epinephrine on plasma volume may be more likely in:
1. Presence of shock
2. Hypotensive states
3. Both
4. Neither
Epinephrine decreases intraocular pressure due to:
1. Decrease in aqueous humor production
2. Facilitation of outflow
3. Both
4. Neither
Administration of epinephrine and selective β₂ agonists tends increase physiological tremor.
1. True
2. False
Epinephrine effect(s) on plasma potassium:
1. Epinephrine administration decreases plasma potassium.
2. Epinephrine effects on plasma potassium are likely mediated by activation of β₂ adrenergic receptors.
3. Both
4. Neither
Possible damage to arterial walls and myocardium associated with large or frequently repeated epinephrine doses (or other sympathomimetic amines) may be mitigated by α and β receptor blockers and calcium channel blockers.
1. True
2. False
Epinephrine administration it appears to facilitate neuromuscular transmission probably because stimulation of α-type adrenergic receptors, in this setting, causes a more rapid increase in neurotransmitter release from the motoneuron.
1. True
2. False
Epinephrine administered systemically result in substantial sweating and pilomotor activity.
1. True
2. False