Medical Pharmacology Practice Questions: Congestive Heart Failure

In considering acute decompensated heart failure (ADHF) and volume management, choose the correct statement(s).
1. IV diuretic administration may relieve heart failure symptoms both rapidly and effectively.
2. In long-term management, patients receiving a loop diuretic may benefit by the addition of a thiazide-class drug, e.g. metolazone.
3. Both
4. Neither
In ADHF, improvement of myocardial contractility is likely beneficial and may be accomplished by which one(s) of the following agents?
1. Direct-acting agents such as dobutamine may be helpful
2. An indirect-acting agent, such as a phosphodiesterase-3 inhibitor, may be helpful
3. Both
4. Neither
For patients receiving a ß-adrenergic antagonist upon hospital admission for ADHF, which one of the following agents would be preferable?
1. Dobutamine
2. Milrinone
Long-term administration of positive inotropic drugs in ADHF increases mortality.
1. True
2. False
Primary indications for inotropic agents (agents which increase myocardial contractility) in the ADHF setting is that of :"
1. bridge therapy" to transplant or left ventricular assist device implantation.
2. Palliation in end-stage heart failure.
3. Both
4. Neither
Short-term use of inotropic agents in acute decompensated heart failure (ADHF) is:
1. Correlated with increased risk of arrhythmia
2. Hypotensive responses
3. Both
4. Neither
In comparing ultrafiltration, technique of fluid removal for ADHF patients with pharmacological intervention:
1. A major clinical study suggested that more severe adverse events were found in the ultrafiltration group.
2. Using serum creatinine evels as an end point, higher creatinine levels (worse) were noted in the ultrafiltration group.
3. Both
4. Neither