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Ibutilide [eye bu' ti lide]

  • Used in patients with atrial fibrillation or flutter.

  • Effective in about 60% of patients with flutter and 30% with atrial fibrillation.

  • Activates a slow inward sodium channel and prolongs action potential duration.

  • Q-T prolongation and Torsades des Pointes (8% in one clinical trial) may occur.

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