Medical Pharmacology Practice Questions: Local Anesthetics

Which one(s) of the following represent characteristics of chloroprocaine?
1. Rapid onset
2. Extended duration
3. Both
4. Neither
Large chloroprocaine epidural or subarachnoid administered doses may be associated with prolonged motor and sensory blockade.
1. True
2. False
More likely to be associated with transient neurologic syndrome (TNS) in spinal anesthesia.:
1. Lidocaine
2. Chloroprocaine
Bupivacaine:
1. This agent may be an agent of choice for epidural analgesia in labor and for postoperative pain management.
2. This agent exhibits a reasonably favorable therapeutic index in terms of neurotoxicity along with very limited transit and neurologic syndrome (TNS) risk.
3. Both
4. Neither
Etidocaine, compared to bupivacaine, administration results in greater motor versus sensor blockade (inverse differential block).
1. True
2. False
Lidocaine is considered a standard against which most local anesthetics are compared and exhibits an excellent record for intermediate duration local anesthesia.
1. True
2. False
Compared to lidocaine, mepivacaine is more likely to exhibit this vascular effect.
1. Vasoconstriction
2. Vasodilation
Ropivacaine is considered a reasonable and frequently chosen local anesthetic for epidural administration in management of both postoperative and labor pain.
1. True
2. False
Lidocaine and prilocaine may be used in combination to cause localized anesthesia as a result of penetrating keratinized skin layers. This combination is useful in pediatrics prior to venipuncture for intravenous catheterization.
1. True
2. False
Tetracaine is frequently employed for spinal anesthesia in cases when long anesthesia duration is required.
1. True
2. False