Medical Pharmacology Practice Questions: Opioid Analgesics

Pain most effectively relieved by opioid analgesics
1. Severe constant pain
2. Intermittent sharp pain
3. Both
4. Neither
In the hospice setting fixed-interval opioid administration appears more effective in managing pain then dosing on demand.
1. True
2. False
There is little clinical evidence supporting greater than six months use of sustained-release opioids e.g. MS Contin (sustained-release morphine) and OxyContin(sustained-release oxycodone) for managing non-cancer related chronic pain.
1. True
2. False
More likely to be effective in avoiding G.I. intestinal dysfunction following administration:
1. Morphine (oral sustained-release)
2. Transdermal fentanyl
3. Both
4. Neither
Effective in reversing neonatal depression if opioid analgesics are used during obstetric labor.
1. A phenylpiperidine drugs such as meperidine
2. Naloxone
A significant relief of dyspnea secondary to pulmonary edema due to left ventricular failure is associated with morphine administration (IV).
1. True
2. False
Factor(s) associated with the efficacy of IV morphine in reducing congestive heart failure-related shortness of breath:
1. Reduced afterload
2. Reduced preload
3. Reduced anxiety
4. A & B
5. B & C
6. A, B & C
Example(s) of opioids used for managing diarrhea:
1. Loperamide
2. Diphenoxylate
3. Both
4. Neither
Meperidine, through acting on an alpha type 2 adrenergic receptor, appears most effective among opioid agonists in reducing shivering.
1. True
2. False
Opioids, such as fat milk, may be a major component, even a primary component,of the anesthesia therapeutic regimen
1. True
2. False