Medical Pharmacology Practice Questions: Anti-Parkinsonism Drugs

Choose which one(s) of the following statements is/are correct concerning the pharmacology of amantadine.
1. Amantadine exhibits antiviral properties
2. Amantadine exhibit significant antiparkinsonian effects
3. Both
4. Neither
Amantadine is both less effective than L-dopa and its effectiveness tends to be of limited duration, perhaps only lasting a few weeks.
1. True
2. False
Dermatological adverse effects including livedo reticularis have been associated with amantadine treatment. Other side effect(s) include/includes:
1. Peripheral edema
2. Postural hypotension
3. Urinary retention
4. A & B
5. B & C
6. A, B & C
Amantadine should be used with caution in patients whose history exhibits susceptibility to seizures.
1. True
2. False
Which one(s) of the following antimuscarinic drugs (anticholinergic) is/are used in the clinical management of parkinsonism?
1. Orphenadrine
2. Benztropine
3. Both
4. Neither
Cholinergic-muscarinic receptor blockers have become widely used in managing Parkinson's disease subsequent to the introduction of levodopa.
1. True
2. False
Some agents are under evaluation as potential "neuroprotective drugs" which may slow parkinsonism progression. Example(s) include/includes:
1. Glutamate antagonists
2. Antiapoptotic drugs
3. Both
4. Neither