Medical Pharmacology Practice Questions: Anti-Psychotic Agents

"Positive" symptoms as a classification of schizophrenia include which one(s) of the following?
1. Anhedonia
2. Avolition
3. Agitation
4. Affective flattening
Cognitive function is one CNS characteristic that remains unaffected by schizophrenia.
1. True
2. False
Hallucinations and delusions represent "positive" symptoms of schizophrenia.
1. True
2. False
Anxiety and depression, given that they are not associated with schizophrenia, respond better to anxiolytic agents.
1. True
2. False
Concerning depression as a presentation of schizophrenia, which one(s) of the following is/are correct?
1. Depression often is exhibited following acute psychotic episodes.
2. Depression may occur and be present independent of positive symptoms and may occur at any stage of schizophrenia.
3. Both
4. Neither
For nearly all patients, antipsychotic medications represent the treatment of choice for management of schizophrenia.
1. True
2. False
The classical, "typical"first-generation antipsychotic medication is chlorpromazine.
1. True
2. False
The CNS receptor system thought to mediate the actions of chlorpromazine:
1. Noradrenergic
2. Dopaminergic (D2)
3. Cholinergic
4. Serotonergic
Chlorpromazine, as an example, is a direct-acting dopamine D2-receptor blocker. Which one(s) of the following statements is/are correct?
1. Excessive dopamine activity in the mesolimbic tract is likely associated with positive symptoms.
2. Reduced dopamine transmission in the mesocortical tract is likely associated with both "negative" symptoms and cognitive dysfunction.
3. Both
4. Neither
The symptom, hyperprolactinemia, is associated with D2 receptor activation in the tuberoinfundibular pathway.
1. True
2. False