Medical Pharmacology Chapter 16:
Anti-Psychotic Drug Practice Questions
lick on the correct answer.
"Positive" symptoms as a classification of schizophrenia include which one(s) of the following?
- Anhedonia
- Avolition
- Agitation
- Affective flattening
Cognitive function is one CNS characteristic that remains unaffected by schizophrenia.
- True
- False
Hallucinations and delusions represent "positive" symptoms of schizophrenia.
- True
- False
Anxiety and depression, given that they are not associated with schizophrenia, respond better to anxiolytic agents.
- True
- False
Concerning depression as a presentation of schizophrenia, which one(s) of the following is/are correct?
- Depression often is exhibited following acute psychotic episodes.
- Depression may occur and be present independent of positive symptoms and may occur at any stage of schizophrenia.
- Both
- Neither
For nearly all patients, antipsychotic medications represent the treatment of choice for management of schizophrenia.
- True
- False
The classical, "typical"first-generation antipsychotic medication is chlorpromazine.
- True
- False
The CNS receptor system thought to mediate the actions of chlorpromazine:
- Noradrenergic
- Dopaminergic (D2)
- Cholinergic
- Serotonergic
Chlorpromazine, as an example, is a direct-acting dopamine D2-receptor blocker. Which one(s) of the following statements is/are correct?
- Excessive dopamine activity in the mesolimbic tract is likely associated with positive symptoms.
- Reduced dopamine transmission in the mesocortical tract is likely associated with both "negative" symptoms and cognitive dysfunction.
- Both
- Neither
The symptom, hyperprolactinemia, is associated with D2 receptor activation in the tuberoinfundibular pathway.
- True
- False