Medical Pharmacology Practice Questions: Anti-Psychotic Agents

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Which one of the following antipsychotic medications is available as a long-acting injectable or "depot" antipsychotic.
1. Thiothixene
2. Risperidone
3. Chlorpromazine
4. Thioxanthene
Which one of the following antipsychotic agents is NOT available in the US as "depot" antipsychotic, long-acting injectable medication?
1. Haloperidol
2. Fluphenazine
3. Clozapine
4. Risperidone
5. Paliperidone palmitate
This route of administration of antipsychotic drugs is associated with lower relapse rates:
1. Long-acting injectable agents (depot antipsychotics)
2. Oral formulations
Adverse effect(s) associated with clozapine:
1. Sedation
2. Reduction in seizure threshold
3. Agranulocytosis
4. Elevated metabolic risk
5. All of the above
ECT (electroconvulsive therapy) is viewed as a last resort intervention for treating refractory schizophrenia and is frequently used.
1. True
2. False
Administration of antipsychotic drugs is considered foundational in schizophrenia treatment.
1. True
2. False
Catatonic manifestations of schizophrenia are most appropriately initially managed by intravenous administration of benzodiazepines.
1. True
2. Falls
Schizoaffective disorders (presenting features of both schizophrenia and affective disorders) represent an indication for antipsychotic drugs.
1. True
2. False
The manic phase of bipolar affective disorder may be treated with lithium or valproic acid supplemented with lorazepam or clonazepamspace ("high-potency benzodiazepines") in milder presentations.
1. True
2. False
Antipsychotic medications may be used in treating, as monotherapy, in acute bipolar depression.
1. True
2. False