Medical Pharmacology Practice Questions: Sedative-Hypnotic Drugs

Which one(s) of the following statements is/are correct?
1. Benzodiazepine doses suitable for inducing sleep have no respiratory effects on normal subjects.
2. At hypnotic doses benzodiazepines may be used without concern in treatment of children
3. .Benzodiazepines should be used with caution in individuals with reduced liver function.
4. A & B
5. A & C
6. B & C
7. A, B & C
At benzodiazepine doses required for endoscopy:
1. Reduction in alveolar ventilation occurs.
2. A respiratory alkalosis is induced.
3. Both
4. Neither
Even in patients with severe COPD (chronic obstructive pulmonary disease), typical benzodiazepine doses required for sleep may behim always used safely.
1. True
2. False
Benzodiazepine administration at hypnotic doses may increase the effect of apneic episodes on:
1. Pulmonary hypertension
2. Alveolar hypoxia
3. Cardiac ventricular load
4. A & B
5. A & C
6. B & C
7. A, B & C
At normal benzodiazepine doses cardiovascular effects are usually minor in normal individuals.
1. True
2. False
This benzodiazepine use cited as the only one in the group incompletely absorbed following oral administration.
1. Lorazepam
2. Clorazepate
3. Diazepam
4. Flurazepam
Which one of the following benzodiazepines is classified as an intermediate-acting drugs (6-24 half-time)?
1. Lorazepam
2. Diazepam
3. Estazolam
4. Eszopiclone
Choose (the) short-acting sedative hypnotic agent(s) (half-time <6 hours):
1. Zolpidem
2. Eszopiclone
3. Both
4. Neither
Choose (the) long-acting agent(s) from the following list:
1. Quazepam
2. Flurazepam
3. Diazepam
4. A & B
5. A & C
6. A, B & C
Benzodiazepines, including active metabolites, are from about 70% to 99% bound to plasma proteins, depending on the particular agent considered.
1. True
2. False