Pneumonia
  • "For the microbiologic diagnosis of pneumonia, by definition, an infiltrate must be present on a chest x-ray.
  • A deeply expectorated sputum sample will yield the causitive organism from 20-80% of the time, depending on the study.
  • Sputum specimens will be rejected by the laboratory if they have >10 epithelial cells per high power field.
  • The reason is that epithelial cells are usually from the upper airway, and have many adherent bacteria (see photomicrograph).
  • These bacteria constitute the normal flora of the upper airway, and confuse interpretation of the culture."
  • Ó 1999- KUMC Pathology and the University of Kansas, used with permission; courtesy of Dr. James Fishback, Department of Pathology, University of Kansas Medical Center.
  • "Here is the Gram stain of your dreams. Lots of polys, <10 epithlial cells per high power field, and lots of Gram-positive cocci (lancet-shaped, even) that make this most likely a pneumococcal pneumonia."
  • Ó 1999- KUMC Pathology and the University of Kansas, used with permission; courtesy of Dr. James Fishback, Department of Pathology, University of Kansas Medical Center.