Clinical Features:
"The
spectrum varies from asymptomatic
carriage to severe diarrhea and
malabsorption.
Acute
giardiasis develops after an incubation
period of 5 to 6 days and usually lasts 1
to 3 weeks.
Symptoms
include;
diarrhea
abdominal pain
bloating
nausea
vomiting.
In chronic
giardiasis the symptoms are recurrent and
malabsorption and debilitation may
occur."
- Laboratory Diagnosis:
"Giardiasis
is diagnosed by the identification of
cysts or trophozoites in the feces, using
direct mounts as well as concentration
procedures.
Repeated
samplings may be necessary.
In
addition, samples of duodenal fluid
(e.g., Enterotest) or duodenal biopsy may
demonstrate trophozoites.
Alternate
methods for detection include antigen
detection tests by enzyme immunoassays,
and detection of parasites by
immunofluorescence.
- Both methods are
available in commercial
kits."
Treatment:
- The Medical Letter
recommends metronidazole (Flagyl) as the
drug of choice, with tinidazole,
furazolidone, and paromomycin as
alternatives.
|