- "Members of the cat family
(Felidae) are the only known definitive hosts for
the sexual stages of T. gondii and thus are the
main reservoirs of infection.
- Cats become infected with T.
gondii by carnivorism.
- After tissue cysts or oocysts are
ingested by the cat, viable organisms are
released and invade epithelial cells of the small
intestine where they undergo an asexual followed
by a sexual cycle and then form oocysts, which
are then excreted.
- The unsporulated oocyst takes 1 to
5 days after excretion to sporulate (become
infective).
- Although cats shed oocysts for
only 1 to 2 weeks, large numbers may be
shed.
- Oocysts can survive in the
environment for several months and are remarkably
resistant to disinfectants, freezing, and drying,
but are killed by heating to 70oC for
10 minutes.
- Human infection may be acquired in
several ways:
- 1) ingestion of
undercooked infected meat containing
Toxoplasma cysts;
- 2) ingestion of the oocyst
from fecally contaminated hands or food;
- 3) organ transplantation
or blood transfusion;
- 4) transplacental
transmission;
- 5) accidental inoculation
of tachyzoites.
- The parasites form tissue
cysts, most commonly in skeletal muscle,
myocardium, and brain; these cysts may
remain throughout the life of the
host."- CDC (used with permission,
public domain)
- http://www.dpd.cdc.gov/DPDx/HTML/Toxoplasmosis.htm
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