Medical Pharmacology Chapter 29: Diabetes Management Practice QuestionsMedical Pharmacology Chapter 29: Diabetes Management Practice Questions

Which one of the following insulin preparations exhibits a relatively longer duration of action?
1. Glulisine (Apidra)
2. Detemir (Levemir)
3. Lispro (Humalog)
4. Aspart (Novolog)
Which one(s) of the following agents is/are classified as having a relatively "longer duration of action" compared to the "very rapid-acting insulins."
1. Degludec (Tresiba)
2. Detemir (Levemir)
3. Glargine (Basaglar)
4. A & B
5. B & C
6. A & C
7. A, B & C
Onset of action of "short-acting" insulin preparations:
1. <25 minutes
2. 40-60 minutes
3. 90 minutes
The onset of action of "Regular" insulin is about 30-60 minutes.
1. True
2. False
Insulin preparation with the shortest effective duration:
1. Degludec
2. Aspart
3. Both are similar
Relatively short-acting insulin analogs exhibit relatively slow absorption from subcutaneous sites compared to regular insulin.
1. True
2. False
Concerning "long-acting insulins," which of the following statement/statements is/are true?
1. NPH insulin (insulin isophane) consists of native insulin complexed with protamine and zinc and phosphate buffer (suspension).
2. Insulin glargine is classified as a long-acting human insulin analog.
3. Both
4. Neither
Insulin detemir is an insulin analog characterized by an attached saturated fatty acid (a.k.a. myristoylated insulin).
1. True
2. False
The hypoglycemic effect associated with insulin degludec appears less prominent compared to that associated with glargine administration.
1. True
2. False
Combinations of short-acting and long-acting insulin formulations are helpful in part by decreasing the frequency of injections per day.
1. True
2. Paul's