Medical Pharmacology Chapter 23: Ergot Pharmacology Practice Questions

Concerning the use of ergotamine tartrate, choose the correct statement/statements.
1. Ergotamine tartrate can be taken orally upon recognition of acute migraine onset symptoms.
2. Ergotamine tartrate may be taken by rectal suppository.
3. Ergotamine tartrate in combination with an oral analgesic-caffeine combination can be taken an hour after initial treatment.
4. A & B
5. B & C
6. A & C
7. A, B & C
Cautious use recommended for ergotamine in this/these circumstances.
1. Patient has hypertension.
2. Patient has peripheral vascular disease.
3. Both
4. Neither
Ergotamine administration is contraindicated in which one(s) of the following circumstances?
1. In pregnant women
2. In patients with coronary artery disease
3. Both
4. Neither
Dihydroergotamine exhibits comparable efficacy compared to sumatriptan after two hours.
1. True
2. Paul's
Potential approach(es) for "status migrainosus." (Status migrainosus refers to a debilitating migraine headache lasting more than 72 hours).
1. Neuroleptic administration (acutely) with or without dihydroergotamine
2. Dihydroergotamine in combination with metoclopramide.
3. Both
4. Neither
Factor/factors associated with status migrainosus and may require inpatient management.
1. Dehydration
2. Sleep deprivation
3. Continued pain
4. A & B
5. B & C
6. A & C
7. A, B & C
ß-adrenergic blockers (antagonists) are commonly used for migraine headache prophylaxis.
1. True
2. False
Propranolol, a nonspecific ß-adrenergic antagonists, is contraindicated in which one(s) of the following?
1. Patients with a history of asthma
2. Patients with a history of severe depression
3. Both
4. Neither
This/these agent(s) probably have about the same benefit in the migraine setting as propranolol
1. Timolol (Betimol, Timoptic)
2. Atenolol (Tenormin)
3. Metoprolol (Lopressor)
4. A & B
5. B & C
6. A & C
7. A, B & C
Some benefit in preventing recurrent migraine is associated with this/these agent(s).
1. Verapamil (Verelan)
2. Flunarizine (Sibelium)
3. Both
4. Neither