Medical Pharmacology Chapter 27: Gastrointestinal Pharmacology Practice Questions

Antacids represented the primary agent for management of acid-peptic disease until:
1. The development of H₂ receptor blockers
2. The development of proton pump inhibitors
3. Both
4. Neither
Use(s) of antacids in the nonprescription setting:
1. Dyspepsia
2. Occasional heartburn
3. Both
4. Neither
Antacids:
1. These agents are weak bases.
2. Antacids react with hydrochloric acid in the stomach forming water and a salt.
3. Both
4. Neither
Difference(s) between different antacid formulations:
1. Dissolution rate
2. Reaction rate with the acid
3. Water solubility
4. A & B
5. B & C
6. A & C
7. A, B & C
Baking soda (sodium bicarbonate) reacts with hydrochloric acid (HCl) resulting in sodium chloride and carbon dioxide production.
1. True
2. False
Administration of sodium bicarbonate and resulting unreacted alkali:
1. May cause metabolic alkalosis (at high doses)
2. May cause metabolic alkalosis in renal insufficiency settings
3. Both
4. Neither
Sodium chloride, consequence of sodium bicarbonate interaction with HCl-clinical consequence(s):
1. Fluid retention in heart failure patients
2. Fluid retention in hypertensive patients
3. Fluid retention in the context of renal insufficiency
4. A & B
5. B & C
6. A & C
7. A, B & C
Compared to sodium bicarbonate, calcium carbonate (Tums):
1. Calcium carbonate is less soluble.
2. Calcium carbonate reacts with HCL more slowly
3. Both
4. Neither
Sodium bicarbonate or calcium carbonate taken in high, excessive doses with calcium-containing dairy
1. Metabolic alkalosis
2. Renal insufficiency
3. Hypercalcemia
4. A & B
5. B & C
6. A & C
7. A, B & C
Antacids may influence, through drug binding, absorption of other agents.
1. True
2. False

Medical Pharmacology: Gastrointestinal Pharmacology Practice Questions