Medical Pharmacology Chapter 27: Gastrointestinal Pharmacology Practice Questions

Concerning dietary fiber in the context of constipation:
1. Fecal hydration as well as bulk and softness depend in part on dietary fiber content
2. Fiber fermentation reduces stool water; however, short-chain fatty acids may be prokinetic and increased bacterial mass is associated with increased stool volume.
3. Both
4. Neither
Dietary fiber composition influences fiber effects on bowel movement. Insoluble, poorly fermentable fiber tend to be most effective in managing constipation.
1. True
2. False
Characteristic(s) all bulk-forming laxatives:
1. Digestible
2. Hydrophilic colloids absorbing water
3. Both
4. Neither
Preparation(s) of bulk-forming laxatives:
1. Methylcellulose
2. Psyllium
3. Both
4. Neither
A synthetic fiber, bulk-forming laxative: polycarbophil
1. True
2. False
Digestion of plant fiber in the colon by bacteria can cause flatus and bloating.
1. True
2. False
Most likely effective in increasing stool bulk and transit.
1. Hemicellulose
2. Mucilages and gums
3. Lignin
Least water-soluble among these different dietary fibers:
1. Hemicellulose
2. Mucilages and gums
3. Cellulose
Bran:
1. More than 40% dietary fiber (residue left when flower is made from cereal grains)
2. Wheat bran: most effective in increasing stool weight.
3. Both
4. Neither
Psyllium husk: component of many constipation products.
1. True
2. False

Medical Pharmacology: Gastrointestinal Pharmacology Practice Questions