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Important anesthetic agents administered as racemic mixtures include:
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Thiopental (pentothal)
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Methohexital (Brevital)
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Ketamine (Ketalar)
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Halothane (Fluothane)
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Enflurane (ethrane)
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Isoflurane (Forane)
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Sevoflurane (Sevorane, Ultane)
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Barbiturates: Structural Analysis: 75% similar structures Pentobarbital sodium (Nembutal) 
Thiopental sodium (Pentothal) 
Butabarbital sodium (Butisol) 
Thiamylal 
Amobarbital sodium 
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Metabolism:-
Many enzymes exhibit stereoselectivity, a preference for one or the other enantiomeric form.
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In the case of drug-metabolizing enzymes, stereoselectivity may result in a difference in the duration of action of one enantiomer compared to the other.
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Structure Activity
Relationships:
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Understanding the relationship between drug structures and biological activities forms the basis of rational drug design.
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Computer-enhanced molecular modeling and information concerning three-dimensional receptor structure may combine to improve the effectiveness of rational drug design approaches.
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Katzung, B. G. "Basic Principles: Introduction" in Basic and Clinical Pharmacology, (Katzung, B. G., ed) Appleton-Lange, 1998, p.1-4
Stoelting, R.K., "Pharmacokinetics and Pharmacodynamics of Injected and Inhaled Drugs", in Pharmacology and Physiology in Anesthetic Practice, Lippincott-Raven Publishers, 1999, 1-17
3Dolin, S. J. "Drugs and pharmacology" in Total Intravenous Anesthesia, pp. 13-35 (Nicholas L. Padfield, ed), Butterworth Heinemann, Oxford, 2000.
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