• produces interferon-g (IFNg)
• produces interleukin-2 (IL-2)
• produces tumor necrosis factor-b (TNFb)
• induces cell-mediated immunity by activation of:
  • cytotoxic T cells (CTL)
  • natural killer (NK) cells
  • macrophages
• IL-10 (from TH2 cells) down regulates TH1 activity

.