Belongs to the class of tumor necrosis factor (TNF-α) antagonists.
This drug
is described as the dimeric fusion protein and consists of (1) an extracellular ligand-binding domain of the tumor necrosis factor receptor (TNFR) linked to the FC component of human IgG1.
Both
Neither
Etanercept (Enbrel): Etanercept (Enbrel) upon binding to TNF-α, prevents TNF-α from binding to its receptor.
True
False
Etanercept (Enbrel):
May be clinically used as single-agent or in combination with methotrexate for management of "severe, active and progressive" rheumatoid arthritis
In rheumatoid arthritis treatment, this agent is used after the arthritic condition
does not respond to other "Disease-modifying antirheumatic drugs" (DMARDS).
Both
Neither
Etanercept (Enbrel): subcutaneous injections into the abdomen or anterior thigh.
True
False
Etanercept pharmacokinetics:
Following subcutaneous administration, drug absorption is slow.
Peak concentrations are realized after about three days
Both
Neither
Acts by targeting subunit of interleukin 12 and interleukin 23:
Ustekinumab (Stelara)
Etanercept (Enbrel)
Both
Neither
Relatively frequently observed adverse effect/effect(s) associated with etanercept administration:
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Source Material:
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