Muromonab (Orthoclone OKT3): approved for use in treating acute renal allograft rejection
True
False
Muromonab (Orthoclone OKT3):
This agent suppresses T-cell function
Given that muromonab is derived from mice, patients who are to receive muromonab are typically pretreated with immunosuppressant agents prior to initiation of muromonab therapy.
Both
Neither
Concerning muromonab CD3 side effects:
Cytokine release syndrome (CRS) is usually associated with the initial doses of this agent.
CRS would be typically seen within 30-60 minutes following the first dose.
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