Medical Pharmacology: Immunopharmacology (Immunosuppressants/Immunomodulators) and Monoclonal Antibodies (mAb) Antiviral Practice Questions
Obiltoxamimab (Anthim) and Raxibacumab (ABthrax):
Bacilllus antracis (Anthrax)
Click on the correct answer.
FDA-approved monoclonal antibody/antibodies for treating patients following Bacillus anthracis spore inhalation.
Obiltoxamimab (Anthim)
Raxibacumab (ABthrax)
Both
Neither
FDA-approved anti-toxin(s) useful for treating inhalational anthrax:
Anthrax immunoglobulin (Anthrasil, Aigiv).
Obiltoxamimab (Anthim)
Raxibacumab
A & B
B & C
A, B & C
Antitoxins are important interventions employed along with antimicrobial treatment.
True
False
Preferred for postexposure prophylaxis (anthrax exposure):
Antimicrobial agents
Antitoxins
Both equally efficacious
In combination with antibacterial agents, approved for treatment/prophylaxis of inhalational anthrax:
Adults
Children
Both
Obiltoxamimab and raxibacumab act by preventing B. anthracis "protective antigen" binding to its cellular receptor thus inhibiting anthrax entry into cells.
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