Medical Pharmacology Chapter 25: Pulmonary Pharmacology Practice Questions

Which one(s) of the following statements concerning methylxanthine effects on the CNS is/are correct?
1. Methylxanthines, notably caffeine, administration results in some cortical arousal with increased alertness.
2. Caffeine in amounts associated with a single cup of coffee (100 mg) may result in some bronchodilation in asthmatic patients.
3. True
4. False
Cardiac methylxanthine effect/effects:
1. Positive chronotropism
2. Positive inotropism
3. Both
4. Neither
Administration of methylxanthines, such as pentoxifylline, reduced blood viscosity with improvement of blood flow in some circumstances.
1. True
2. False
Theophylline administration may induce a weak diuresis. This effect is associated with which one(s) of the following?
1. Increased tubular reabsorption
2. Increased glomerular filtration
3. Both
4. Neither
Methylxanthine effects/effects on skeletal muscle:
1. Improve skeletal muscle contractility
2. Reverse diaphragmatic fatigue in COPD patients
3. Both
4. Dear
In the xanthine category, theophylline is classified as the most effective bronchodilator.
1. True
2. False
Antimuscarinic drugs have been shown to be effective bronchodilators.
1. True
2. False
Which one of the following antimuscarinic drugs are less likely to exhibit systemic effects following aerosol administration?
1. Atropine
2. Ipratropium
3. Both about the same
In COPD patients with that minimum partially reversible obstruction, ipratropium (antimuscarinic) is comparably effective as albuterol.
1. True
2. False
Which one(s) of the following long--acting antimuscarinic drugs have been approved for COPD maintenance treatment?
1. Tiotropium (Spiriva)
2. Aclidinium (Bretaris Genuair and others)
3. Umeclidinium (Incruse Ellipta)
4. A & B
5. B & C
6. A, B & C