Medical Pharmacology: Renal Pharmacology Practice Questions
Choose the correct answer for each question.
Most effective of the currently available diuretic drugs:
- Thiazide diuretics
- Loop diuretics
- Carbonic anhydrase inhibitors
- Osmotic diuretics (e.g. mannitol)
This diuretic is described as a phenoxyacetic acid derivative.
- Torsemide
- Ethacrynic acid
- Both
- Neither
Principal site of action of bumetanide:
- Collecting duct
- Proximal tubule
- Thick ascending loop of Henle
- Distal tubule
Which drug in the following list is NOT a sulfonylurea or an agent containing a sulfonamide moiety?
- Furosemide (Lasix)
- Bumetanide (Bumex)
- Torsemide (Demadex)
- Ethacrynic acid (Edecrin)
Loop diuretics are also called "high-ceiling diuretics."
- True
- False
Which one(s) of the following is/are correct?
- Furosemide is available as an oral and injectable agent
- .Bumetanide is available as an oral and injectable formulation.
- True
- False
Ethacrynate sodium is available in injectable form.
- True
- False
Concerning the pharmacokinetics of loop diuretics, choose which one(s) of the following statements is/are correct.
- Loop diuretics are eliminated by glomerular filtration and tubular secretion
- Loop diuretics are typically absorbed rapidly.
- Both
- Neither
Concerning the loop diuretic torsemide:
- Oral torsemide is absorbed more rapidly compared to furosemide.
- Compared to torsemide, bumetanide pharmacokinetics appear similar; however, bumetanide is notably more potent in its activity as a loop diuretic.
- Both
- Neither
Longer duration of action:
- Torsemide
- Furosemide
- Neither, both agents have the same duration of action
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