Medical Pharmacology: Renal Pharmacology Practice Questions
Choose the correct answer for each question.
The more potent diuretic:
Thiazide diuretics
Carbonic anhydrase inhibitors
Both are about equally potent
In terms of The "prototypical" drug associated with the thiazide class of diuretics: the prototype thiazide is hydrochlorothiazide (HCTZ).
True
False
Thiazide diuretics:
This term refers to inhibitors of Na+-Cl- symport inhibitors
An example of a thiazide diuretic is chlorothiazide.
An example of a thiazide-like diuretic is indapamide.
A & B
B & C
A & C
A, B & C
This drug is classified as a "thiazide-like diuretic" as opposed to a thiazide diuretic.
Bendroflumethiazide
Methylclothiazide
Metolazone
Chlorothiazide
Referencing hydrochlorothiazide as having a relative potency of 1, this agent exhibits the highest relative potency.
Bendroflumethiazide
Chlorothalidone
Indapamide
Chlorothiazide
The primary route of elimination of which one(s) of the following is solely by metabolism.
Methylclothiazide
Indapamide
Both
Neither
The primary route of elimination of which one(s) of the following agents is/are solely by renal excretion.
Chlorothiazide
Hydrochlorothiazide
Both
Neither
The route of elimination of bendroflumethiazide is primarily by metabolism (about 70%) and by renal excretion (about 30%).
True
False
The primary route of elimination of metozalone is mainly renal (about 80%) as well as about 10% by metabolism and about 10% by biliary excretion of intact drug.