Medical Pharmacology Chapter 26: Renal Pharmacology Practice Questions

Hypokalemic metabolic alkalosis observed with which one(s) of the following?
1. Thiazide diuretics
2. Loop diuretics
3. Both
4. Neither
Thiazide diuretics and diabetes: which one(s of the following statements is/are correct?
1. Administration of thiazide diuretics may induce hyperglycemia.
2. Thiazide diuretics impair pancreatic insulin release
3. Both
4. Neither
Thiazide diuretics reduce tissue utilization of glucose.
1. True
2. False
Thiazide diuretics inhibit insulin release by inducing hyperpolarization of beta cells.
1. True
2. False
Effects/effects of thiazide diuretics on lipidemic state:
1. Increase in total serum cholesterol
2. Decrease in low-density lipoprotein (LDLs)
3. Both
4. Neither
Thiazide diuretic administration can result in hyponatremia.
1. True
2. False
Hyponatremia classified as an important adverse effect associated with thiazide diuretic administration: cause(s)
1. Increase in antidiuretic hormone (ADH) due to hypovolemia
2. Increased thirst
3. Reduction in renal diluting capacity
4. A & B
5. B & C
6. A & C
7. A, B & C
Thiazides among the diuretic classes is the diuretic class most associated with the development of gout.
1. True
2. False
Cross-reactivity of thiazides might be expected with drugs belonging to this group:
1. Tetracyclines
2. Sulfonamides
3. Butyrophenones
Allergic reactions albeit very rare include which one(s) of the following?
1. Acute necrotizing pancreatitis
2. Hemolytic anemia
3. Thrombocytopenia
4. A & C
5. A, B & C