Medical Pharmacology: Thyroid Pharmacology Practice Questions

Medical Pharmacology: Thyroid Pharmacology Practice Questions

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Thyrotoxicosis synonym(s):
1. Thyroid hormone excess
2. Hyperthyroidism
3. Both
4. Neither
Thyrotoxicosis in the absence of hyperthyroidism:
1. Subacute thyroiditis
2. Thyroid destruction due to for example, amiodarone administration or radiation.
3. Silent thyroiditis
4. A & B
5. B & C
6. A & C
7. A, B & C
Primary hyperthyroidism:
1. TSH-secreting pituitary adenoma
2. Graves' disease
3. Both
4. Neither
Secondary hyperthyroidism:
1. TSH-secreting pituitary adenoma
2. Gestational thyrotoxicosis
3. Chorionic gonadotropin-secreting tumors
4. A & B
5. B & C
6. A & C
7. A, B & C
Graves' disease:
1. About 60%-80% of thyrotoxicosis results from Graves' disease.
2. Factors that influence population prevalence involve both genetic factors and iodine intake.
3. Both
4. Neither
Symptom/symptoms of thyrotoxicosis:
1. Heat intolerance
2. Fatigue and weakness
3. Both
4. Neither
Symptom/symptoms of thyrotoxicosis:
1. Polyuria
2. Diarrhea
3. Both
4. Neither
Symptom/symptoms of thyrotoxicosis:
1. Increased appetite associated with weight loss
2. Palpitations
3. Both
4. Neither
Sign(s) of thyrotoxicosis:
1. Tremor
2. Goiter
3. Both
4. Neither
Sign(s) of thyrotoxicosis:
1. Lid retraction
2. Cold dry skin
3. Both
4. Neither

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Source Material:
- Koenig RJ Brent GA Chapter 47 Thyroid and Antithyroid Drugs In Goodman & Gilman's The Pharmacological Basis of Therapeutics (Brunton LL Knollman BC eds) McGraw Hill LLC (2023).
- Jameson JL Mandel SJ Weetman AP Ch 383 Hypothyroidism in Harrison's Principles of Internal Medicine, 21e McGraw Hill 2022.
- Jameson JL Mandel SJ Weetman AP Ch 384 Hyperthyroidism and Other Causes of Thyrotoxicosis in Harrison's Principles of Internal Medicine, 21e 2022.
- Hershman JM Human chorionic gonadotropin and the thyroid: hyperemesis gravidarum and trophoblastic tumors . Thyroid Jul, 9( 7): 653-657 1999. https://pubmed.ncbi.nlm.nih.gov/10447009/
- Bong BJ Thyroid Drugs & Anti-thyroid Drugs Ch 38 in Katzung's Basic & Clinical Pharmacology (Vanderah TW, ed) 16e McGraw Hill 2023.
- Jonklaas J Cooper DS Ch 213 Thyroid in Goldman-Cecil Medicine E-Book (Goldman L Schafer AI, eds) 26e Elsevier 2020.
- Ritter JM Flower R Henderson G Loke YK MacEwan D Robinson E Fullerton J Chapter 53 Antiviral Drugs Rand & Dale's Pharmacology 10e Elsevier 2024.
- Hollenberg A Chin WW Pharmacology of the Thyroid Gland Chapter 28 in Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. (Golan DE Armstrong EJ Armstrong AW, eds) 4e 2017.