Nursing Pharmacology: Antibacterial Drug Practice Questions

Notably broad spectrum of activity against gram-negative bacteria (including Pseudomonas aeruginosa (P. aeruginosa)
1. Ofloxacin
2. Ciprofloxacinb
3. Levofloxacin
4. A & B
5. B & C
6. A & C
7. A, B & C
Resistance associated with fluroquinolone management of serious pseudomonal infections, these agents are typically combined with antipseudomonal ß-lactams.
1. True
2. False
Levofloxacin, moxifloxacin, gemifloxacin, delafloxacin:
1. Exhibit gram -positive activity against Streptococcus pneumoniae (S. pneumoniae) and some strains of MSSA (Meticillin-Sensitive-Staphyloccus aureus).
2. The above agents except for delafloxacin may be used in treating community-acquired pneumonia.
3. Both
4. Neither
Typically, strains of methicillin-resistant Staphylococcus aureus (MRSA) exhibit resistance to the action of fluoroquinolones except for delafloxacin.
1. True
2. False
Fluoroquinolones may be effective in treating bacterial prostatitis given fluroquinolone penetration into prostate tissue.
1. True
2. False
Gatifloxacin, gemifloxacin, moxifloxacin and delafloxacin:
1. Set of fluoroquinolones with enhanced antibacterial activity with respect to gram-positive organisms, notably Staphylococcus pneumoniae and some staphylococci.
2. Delafloxacin among the above four drugs exhibits antibacterial activity similar to ciprofloxacin with respect to gram-negative bacteria.
3. Both
4. Neither
Gatifloxacin is an example of a fluroquinolone only available as an ophthalmic solution (USA).
1. True
2. False
Moxifloxacin, due to a tendency to slightly prolong the myocardial QTc interval, should likely be used cautiously in individuals receiving additional QTc-prolonging agents.
1. True
2. False
Examples of adverse effects associated with fluroquinolone administration include/includes:
1. CNS effects (including seizures)
2. Peripheral neuropathy
3. Both
4. Neither
Examples of adverse effects associated with fluroquinolone administration include/includes:
1. Tendinopathy involving Achilles tendon rupture notably in older patients and patients also receiving glucocorticoids.
2. Possibly associated with enhance risk of aortic aneurysm due to fluroquinolone effects on connective tissue.
3. Both
4. Neither