Group of endogenous proteins that exhibit antiviral activities;

First available reverse transcriptase drug for treatment of HIV-1; a deoxythymidine analogue

Synthetic analog of deoxyadenosine; active triphosphate form inhibits viral replication by competitively inhibiting HIV reverse transcriptase and by chain termination;may be prescribed concurrently with zidovudine or given as monotherapy; major clinical toxicity is a dose-dependent pancreatitis.

Foscarnet (Foscavir): Adverse reactions:

HIV protease inhibitor

Likely to promote drug-drug interactions because of interactions with cytochrome P-450 drug metabolizing systems.

Most likely to cause additive myelosuppresion in an HIV patient also receiving ganciclovir for CMV retinitis:

HIV drug treatment most likely to chang serum concentrations of fluoxetine (Prozac).

Used to treat HSV:

HIV reverse transcriptase inhibitor