Nursing Pharmacology:
Autonomic Pharmacology Practice Questions
Click on the correct answer.
Drugs activating this receptor are used in treating asthma:
- beta1 adrenergic
- muscarinic cholinergic
- beta2 adrenergic
- nicotinic cholinergic
Epinephrine effects on the heart
- increased rate
- decreased contractility
- coronary vasodilation
- A & C
Receptor activation mainly responsible for positive inotropism:
- alpha1
- beta1
- dopamine D1
- muscarinic cholinergic
Epinephrine effects on respiration:
- stimulation
- inhibition
Activates alpha receptors
- isoproterenol (Isuprel)
- propranolol (Inderal)
- phenylephrine (Neo-Synephrine)
- terbutaline (Brethine)
Blocks cardiac isoproterenol effects
- terbutaline (Brethine)
- esmolol (Brevibloc)
- atropine
- mecamylamine (Inversine)
Alpha agonist: vasoconstriction and elevates blood pressure:
- metoprolol (Lopressor)
- methoxamine (Vasoxyl)
- terbutaline (Brethine)
- ipratropium (Atrovent)
Nerve terminal reuptake inhibitor
- methoxamine (Vasoxyl)
- cocaine
- reserpine
- timolol (Blocadren)
Alpha adrenoceptor COVALENT blocker:
- propranolol (Inderal)
- phenoxybenzamine (Dibenzyline)
- phentolamine (Regitine)
- pilocarpine (Pilocar)
Orthostatic (postural) hypotension
- beta receptor activation
- alpha receptor activation
- alpha receptor blocker
- dopamine receptor blockade
Norepinephrine pressor response blocked by:
- mecamylamine (Inversine)
- prazosin (Minipress)
- atropine
- propranolol (Inderal)
Bronchodilation
- ipratropium (Atrovent)
- timolol (Blocadren)
- albuterol (Ventolin,Proventil)
- A & C
Positive chronotropic effects of epinephrine:
- increased SA nodal potassium current
- beta1 receptor activation
- mediated by G protein
- B & C
Maximal ß-adrenergic receptor desensitization depends on:
- receptor occupancy by agonists
- an arrestin protein
- receptor phosphorylation
- A, B & C
Phase of the cardiac action potential that principally determine heart rate
- phase 0
- phase 4
- phase 2
- phase 3
Most likely to increase myocardial afterload
- angiotensin converting enzyme inhibitor (decreases angiotensin II concentration)
- propranolol (Inderal)
- phenylephrine (Neo-Synephrine)
- low-dose epinephrine
Pressor effects of epinephrine are blocked by this drug ("epinephrine reversal")
- propranolol (Inderal)
- phentolamine (Regitine)
- phenylephrine (Neo-Synephrine)
- metoprolol (Lopressor)
Decreases blood pressure
- propranolol (Inderal)
- mecamylamine (Inversine)
- phentolamine (Regitine)
- all of the above
Specific alpha2 receptor agonist
- phenoxybenzamine (Dibenzyline)
- propranolol (Inderal)
- guanfacine (Tenex)
- methoxamine (Vasoxyl)
Centrally-acting antihypertensive drug
- nitroprusside sodium (Nipride)
- clonidine (Catapres)
- methoxamine (Vasoxyl)
- captopril (Capoten)