Question # 1 (Multiple Choice) This catecholamine simultaneously can increase myocardial contractility, glomerular filtration rates, sodium excretion, urinary output, and renal blood flow:

A) phenylephrine (Neo-Synephrine)
B) isoproterenol (Isuprel)
C) dobutamine (Dobutrex)
D) dopamine (Intropin)
E) epinephrine

Question # 2 (Multiple Answer) Clinical uses of for propranolol:

A) treatment of essential hypertension
B) management of angina
C) management of certain arrhythmias
D) prophylactic against asthma attacks

Question # 3 (Multiple Choice) Most cardioselective beta1 adrenergic receptor antagonist

A) esmolol (Brevibloc)
B) metoprolol (Lopressor)
C) atenolol (Tenormin)
D) propranolol (Inderal)
E) timolol (Blocadren)

Question # 4 (Multiple Choice) Mechanisms by which epinephrine increases blood pressure:

A) positive chronotropism
B) positive inotropism
C) vasoconstriction
D) all of the above

Question # 5 (Multiple Choice) Primary therapeutic use for alpha2 selective adrenergic agonists:

A) management of arrhythmias
B) management of renal insufficiency
C) management of intraoperative hypotensive states
D) management of hypertension
E) management of Raynaud's phenomenon

Question # 6 (Multiple Answer) Examples of metabolic effects (often adverse effects) associated with beta adrenergic receptor antagonists:

A) speeds recovery from insulin-induced hypoglycemia
B) decreases awareness of hypoglycemic symptom onset
C) increases blood lipid levels

Question # 7 (Multiple Choice) Receptors that mediate most of epinephrine's cardiac effects:

A) beta1 adrenergic
B) beta2 adrenergic
C) dopaminergic
D) alpha-adrenergic

Question # 8 (Multiple Choice) Methoxamine-induced bradycardia could be blocked by administration of:

A) pilocarpine (Pilocar)
B) labetalol (Trandate, Normodyne)
C) esmolol (Brevibloc)
D) atropine
E) edrophonium (Tensilon)

Question # 9 (Multiple Choice) Substantial bradycardia observed in the presence of inhaled anesthetics with this beta adrenergic receptor antagonist

A) propranolol (Inderal)
B) esmolol (Brevibloc) and
C) labetalol (Trandate, Normodyne)
D) timolol (Blocadren)
E) metoprolol (Lopressor)

Question # 10 (Multiple Choice) Dangerous bronchiolar constriction would be most prominent with this beta adrenergic receptor blocker:

A) metoprolol (Lopressor)
B) esmolol (Brevibloc)
C) atenolol (Tenormin)
D) pindolol (Visken)

Question # 11 (Multiple Choice) Primary effect of epinephrine on respiratory tract smooth muscle:

A) smooth muscle constriction
B) smooth muscle relaxation

Question # 12 (Multiple Choice) Typical heart rate response following methoxamine administration:

A) increase
B) decrease

Question # 13 (Multiple Answer) Alpha2 selective adrenergic agonists:

A) phentolamine (Regitine)
B) clonidine (Catapres)
C) guanabenz (Wytensin)
D) phenoxybenzamine (Dibenzyline)
E) methyldopa (Aldomet)

Question # 14 (Multiple Choice) Propranolo loften decreases amide local anesthetic clearance by

A) decreasing hepatic blood flow
B) inhibiting hepatic metabolism of local anesthetic
C) both
D) neither

Question # 15 (Multiple Choice) Additive cardiovascular effects with inhaled anesthetics and bayonet adrenergic receptor blockers greatest with:

A) halothane (Fluothane)
B) sevoflurane (Sevorane, Ultane)
C) desflurane (Suprane)
D) isoflurane (Forane)
E) enflurane (Ethrane)

Question # 16 (Multiple Choice) Propranolol (after chronic administration) would reduce significant first pass uptake of fentanyl at this anatomical site:

A) liver
B) kidney
C) lung
D) spleen
E) gastrointestinal tract

Question # 17 (Multiple Choice) Concerning low-dose dopamine: interaction with this receptor causes renal, mesenteric, and coronary vasodilation:

A) beta1 adrenergic receptors
B) beta2 adrenergic receptors
C) dopamine D1 receptors
D) alpha-adrenergic
E) prostaglandin receptors

Question # 18 (Multiple Answer) beta1 selective adrenergic receptor antagonist

A) propranolol (Inderal)
B) timolol (Blocadren)
C) nadolol (Corgard)
D) metoprolol (Lopressor)
E) atenolol (Tenormin)

Question # 19 (Multiple Answer) Direct cardiac responses to epinephrine:

A) increase contractility
B) increased rate of isometric muscle tension development
C) increased slope of phase 4 depolarization
D) decreased automaticity

Question # 20 (Multiple Answer) Examples of beta2 adrenergic selective agonists:

A) epinephrine
B) isoproterenol (Isuprel)
C) terbutaline (Brethine)
D) albuterol (Ventolin,Proventil)
E) metaproterenol (Alupent)

Question # 21 (Multiple Choice) Beta-receptor antagonist primarily used for the treatment of glaucoma:

A) esmolol (Brevibloc)
B) propranolol (Inderal)
C) nadolol (Corgard)
D) timolol (Blocadren)
E) pilocarpine (Pilocar)

Question # 22 (Multiple Choice) Beta adrenergic receptor blockers:effects on the heart

A) increase heart rate
B) decrease AV node refractory period
C) reduce contractility
D) increase phase 4 depolarization

Question # 23 (Multiple Answer) Direct acting vasoconstrictors:

A) phenylephrine (Neo-Synephrine)
B) metaraminol (Aramine)
C) mephentermine (Wyamine) and
D) methoxamine (Vasoxyl)

Question # 24 (Multiple Answer) Epinephrine: therapeutic uses

A) rapid relief of respiratory distress due to bronchospasm
B) topical hemostasis
C) cardiopulmonary resuscitation
D) reversal of hypersensitivity reactions

Question # 25 (Multiple Answer) Primary mechanism by which norepinephrine acutely increases BP:

A) increases intravascular volume
B) increases heart rate
C) vasoconstriction at precapillary resistance muscles and veins
D) increases angiotensin II plasma levels

Question # 26 (Multiple Answer) Principal receptors activated by norepinephrine:

A) alpha-adrenergic
B) beta1 adrenergic
C) beta2 adrenergic

Question # 27 (Multiple Answer) beta-2 adrenergic receptor-selective agonist(s):may be used in management of both chronic and acute asthma

A) ritodrine (Yutopar) and
B) terbutaline (Brethine)
C) albuterol (Ventolin,Proventil)
D) propranolol (Inderal)
E) timolol (Blocadren)

Question # 28 (Multiple Answer) Vascular effects of norepinephrine:

A) increases total peripheral resistance; often inducing reflex bradycardia
B) blood flow reduction to the kidney
C) maintenance of glomerular filtration rates
D) may increase coronary blood flow (secondary to increase blood pressure and reflex activity)

Question # 29 (Multiple Choice) Perioperative use of this selective beta adrenergic receptor antagonist in patients with significant underlying coronary heart disease may reduce the incidence of cardiovascular complications

A) atenolol (Tenormin)
B) propranolol (Inderal) and
C) metoprolol (Lopressor)
D) esmolol (Brevibloc)
E) timolol (Blocadren)

Question # 30 (Multiple Choice) beta adrenergic receptor antagonist that also blocks alpha receptors

A) timolol (Blocadren)
B) esmolol (Brevibloc)
C) labetalol (Trandate, Normodyne)
D) propranolol (Inderal)
E) nadolol (Corgard)