Vasodilators: Question set #2

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Decreased oxygenation & nitric oxide response:
1. increased NO production
2. decreased NO production
3. no effect on NO production
Comparing arteries & veins: nitric oxide production
1. veins produce more
2. arteries produce more
3. equal
Nitric oxide half-life:
1. < 5 seconds
2. thirty seconds
3. one-minute
4. thirty minutes
5. > one-hour
Clinical uses of nitric oxide
1. management of pulmonary hypertension newborn
2. adult respiratory distress syndrome
3. management of pulmonary hypertension following cardiopulmonary bypass
4. B & C
5. A, B & C
Involvement of nitric oxide and immune function:
1. suppression of macrophage activation by cytokines
2. modulation of inflammation
3. both
4. neither
Nitric oxide mainly inactivated by:
1. NO synthase
2. reuptake
3. interaction with hemoglobin
4. monoamine oxidase
5. catechol-O-methyltransferase
cardiovascular system: nitric oxide effects
1. continual NO release associated with flow-induced shear stress
2. intermittent NO release associated with pulsatile arterial flow
3. significant determinant of pulmonary distribution of cardiac output
4. A & C
5. A, B & C
Nitric oxide & platelet aggregation and adhesion:
1. nitric oxide inhibits platelet aggregation and adhesion
2. nitric oxide promotes platelet aggregation and adhesion
3. no effect
Probable site -- NO as neurotransmitter:
1. neuromuscular junction
2. innervation of the corpora cavernosa
3. basal ganglia
4. Renshaw cell
Agents which may promote coronary vasodilation:
1. beta-blockers
2. calcium channel blockers
3. both
4. neither
Nitric oxide: precursor amino acid --
1. tyrosine
2. tryptophan
3. arginine
4. proline
5. phenylalanine
Nitric oxide -- homeostatic activities:
1. cardiovascular tone
2. platelet regulation
3. gastrointestinal smooth muscle contraction
4. A & B
5. A, B & C