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Bretylium [bre til' ee um]
(Class III, Potassium Channel Blocker):
  • Antiarrhythmic effect due to prolongation of the cardiac action potential and inhibition of norepinephrine reuptake by sympthetic nerves

  • Bretylium infusions are used to treat ventricular fibrillation in emergent circumstances with the aim of control and prevention of recurrence. No longer a first-line agent.