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Ibutilide [eye bu' ti lide]
  • used in patients with atrial fibrillation or flutter

  • effective in about 60% of patients with flutter and 30% with atrial fibrillation.

  • activates a slow inward sodium channel and prolongs action potential duration.

  • Q-T prolongation and Torsades des Pointes (8% in one clinical trial) may occur.