Guided Practice: Antipsychotics #1

Side effects include anti-cholinergic, anti-adrenergic and extrapyramidal
1. chloral hydrate (Noctec)
2. haloperidol (Haldol)
3. lithium
4. meprobamate (Miltown)
Neurochemical abnormality most closely associated with schizophrenia:
1. abnormal glycine metabolism
2. decreased brain GABA
3. dopaminergic abnormality
4. high levels of CNS VMA
Antipsychotic most appropriate in elderly patients with prostatic hypertrophy and chronic constipation.
1. clozapine (Clozaril)
2. thioridazine (Mellaril)
3. haloperidol (Haldol)
4. chlorpromazine (Thorazine)
Least extrapyramidal side effects:
1. haloperidol (Haldol)
2. loxapine (Loxitane)
3. clozapine (Clozaril)
A schizophrenic patient has been treated with haloperidol, loxapine, thiothixene and lithium. If paranoid delusions persist, what other drug might be tried?
1. trifluoperazine (Stelazine)
2. clozapine (Clozaril)
3. benztropine (Cogentin)
4. molindone (Moban)
Patient treated with fluphenazine presents the following day with a unilateral stiff , sore neck and back; What was the neurological reaction--which drug treatments might be appropriate?
1. tardive dyskinesia: reduce fluphenazine (Prolixin) dosage
2. acute dystonia: benztropine (Cogentin)
3. acute dystonia:L-DOPA
4. acute dystonia: diphenhydramine (Benadryl)
Most common antipsychotic neurological side effect:
1. tardive dyskinesia
2. perioral tremor
3. akathisia
4. pseudoparkinsonism
Effective in treating acute dystonia caused by antipsychotic drugs:
1. trihexyphenidyl (Artane)
2. biperiden (Akineton)
3. amantidine (Symmetrel)
4. all of the above
Effective in managing rapidly cycling bipolar diorder in lithium non-responding patient populations:
1. valproic acid (Depakene, Depakote)
2. triazolam (Halcion)
3. dexamethasone (Decadron)
4. all of the above
Accepted first alternative for treating patients with bipolar disorder not adequately responsive to lithium.
1. chlorpromazine (Thorazine)
2. carbamazepine (Tegretol)
3. phenelzine (Nardil)
4. amantidine (Symmetrel)