Nursing Pharmacology Practice Questions

Valium (diazepam) acts through this receptor system:
1. aspartate
2. GABA
3. acetylcholine
4. glutamate
5. serotonin
In the presence of this type of antagonist, antagonism cannot be overcome by increasing agonist concentrations.
1. competitive
2. noncompetitive
G protein coupled receptors are involved in signal transduction for the following:
1. biogenic amines
2. peptide hormones
3. both
4. neither
Regulatory molecules influenced by G protein systems:
1. adenylyl cyclase
2. phospholipase A2,C,D
3. calcium, potassium, sodium ion channels
4. transport proteins
5. all the above
Means by which physiological effects due to cAMP-dependent processes are terminated:
1. reuptake
2. requires gene regulation change
3. cAMP degradation
4. A & B
5. A, B & C
Inhibitors of cyclic nucleotide phosphodiesterases (enzymes that degrade cyclic AMP)
1. caffeine
2. theophylline
3. both
4. neither
Pharmacological actions of which one(s) of the following may be mediated by nitric oxide release
1. serotonin
2. norepinephrine
3. bradykinin
4. A & C
5. A, B & C
Effect of nitric oxide on vascular smooth muscle:
1. contraction
2. relaxation
Refers to drug concentration producing 50% of that drug's maximal effect:
1. LD50
2. Kd
3. EC50
4. TI