Nursing Pharmacology Chapter 21:
Histamine Pharmacology Practice Questions
Click on the correct answer.
H2 Blocker most likely to inhibit P450 drug metabolizing system:
- ranitidine (Zantac)
- cimetidine (Tagamet)
- famotidine (Pepcid)
- nizatidine (Axid)
- all inhibit equally
H2 blocker most likely to cause gynecomastia:
- ranitidine (Zantac)
- famotidine (Pepcid)
- cimetidine (Tagamet)
- nizatidine (Axid)
- clonidine (Catapres)
Most likely to be effective and used in current therapy for duodenal ulcer
- atropine
- scopolamine
- famotidine (Pepcid)
- cyproheptadine (Periactin)
- diphenhydramine (Benadryl)
Example of second-generation antihistamine:
- cyclizine (Marezine)
- diphenhydramine (Benadryl)
- astemizole (Hismanal)
- cyproheptadine (Periactin)
- doxylamine
Antihistaminic most likely to exhibit anticholinergic activity:
- dimenhydrinate (Dramamine)
- astemizole (Hismanal)
- fexofenadine (Allegra)
- terfenadine (Seldane)
- loratidine (Claritin)
The most important pathophysiologic mechanism of mast cell and basophil histamine release:
- chemical (i.e. morphine)
- mechanical cell injury
- immunologic
Non-neuronal site(s) of histamine storage and release:
- basophils
- enterochromaffin-like cells
- mast cells
- A & C
- A, B & C
Histamine aerosol: effects on pulmonary function --
- bronchoconstriction
- bronchodilation
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